Clonal Rearrangements of Antigen Receptor Genes in the Diagnosis of Lymphoid Neoplasia
نویسنده
چکیده
Background Information A clonal population of cells is defined as those cells arising from the mitotic division of a single somatic cell. The somatic mutation theory of carcinogenesis contends that a tumor results from the progeny of a single cell having acquired one or more somatic mutations [1]. Therefore, one of the most important features identifying a cell as being neoplastic is its clonal origin or derivation from a single cell [2].
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تاریخ انتشار 2004